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Boll Soc Ital Biol Sper. 1982 Apr 30;58(8):491-6.

[Inhibition of fructose-induced hyperuricacidemia by pretreatment with phosphates].

[Article in Italian]


To test the hypothesis that intravenous injections of fructose rapidly decreases liver ATP and Pi and results in the rapid degradation of adenine nucleotides and hyperuricemia, fructose was administered intravenously to a group of normal and gouty subjects; 4 gouty patients were treated with a phosphate solution prior fructose loading. The results obtained show that fructose administration plus phosphate solution prevents Pi depletion and inhibits fructose-induced hyperuricemia.

[Indexed for MEDLINE]

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