Format

Send to

Choose Destination
Transplantation. 1980 Aug;30(2):90-6.

Regression on oxymetholone-induced hepatic tumors after bone marrow transplantation in aplastic anemia.

Abstract

Treatment of acquired aplastic anemia with androgens has been occasionally associated with the development of hepatic tumors. We have studied a 13-year-old boy with idiopathic aplastic anemia in whom oxymetholone treatment was associated with a partial hematological remission. Thirty-four months later, however, the patient developed multiple hepatic tumors. When oxymetholone therapy was discontinued, the aplastic anemia relapsed. He then underwent bone marrow transplantation from his HLA-A, B, and D-compatible sibling. This was followed by hematological and immunological reconstitution. The hepatic tumors underwent progressive regression after bone marrow transplantation. The patient is now 3 years post-bone marrow transplantation and is in complete remission of his aplastic anemia with no evidence of detectable liver tumors.

PMID:
7010713
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center