Format

Send to

Choose Destination
See comment in PubMed Commons below
Trans R Soc Trop Med Hyg. 1980;74(4):542-4.

IgM antibody to filarial antigens in human cord blood: possibility of transplacental infection.

Abstract

In a hospital in Sri Lanka, antifilarial antibody in maternal and umbilical cord blood was determined by indirect immunofluorescence, enzyme-linked immunosorbent assay and radio-immunoassay. Anti-filarial antibody was detected in 18 of 340 cord blood samples. Specific IgM antibody was detected in 12 cord blood samples. The foetal IgM antibody was probably in response to a transplacental transfer of filarial antigens. The exposure of the foetus to filarial antigens might be beneficial, increasing resistance to infection, or detrimental by inducing at least partial tolerance.

PMID:
7003833
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center