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Am J Optom Physiol Opt. 1982 Dec;59(12):954-60.

Chromatic and luminosity processing in retinal disease.

Abstract

Color vision loss can be an early sign of eye disease; in many retinal disorders the loss precedes any change in visual acuity. Noninvasive psychophysical methods allow factoring out of preretinal, receptoral, and postreceptoral (neural) components of the color vision change. A loss of chromatic but not achromatic sensitivity occurs for diabetics; the loss is selective for pathways subserving blue-sensitive photoreceptors. Both chromatic and achromatic pathways are altered in glaucoma and senile macular degeneration; the most marked change in central serous choroidopathy is loss of sensitivity somewhere in the blue-sensitive cone pathway. There is evidence that the pathways subserved by blue-sensitive cones have anatomically and physiologically different properties from those served by other receptor types, and they appear particularly vulnerable to disturbances of retinal integrity.

PMID:
6984290
[PubMed - indexed for MEDLINE]
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