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J Am Acad Dermatol. 1980 Jul;3(1):30-5.

Sunscreens prevent ultraviolet photocarcinogenesis.

Abstract

Sunscreens of low or high sun protection factors (SPF*) were tested for their ability to inhibit ultraviolet (UV) carcinogenesis in two varieties of hairless mice. Low protection (SPF = 2) reduced by 50% the number of albino animals developing tumors. High protection (SPF =15) prevented tumor formation. Tumorigenesis was totally prevented in the lightly pigmented variety with either sunscreen, demonstrating the added protection of melanin. In mice and man, UV-induced cancer is a cumulative process. Reducing the amount of UV light reaching the basal layer will retard that process.

PMID:
6967495
DOI:
10.1016/s0190-9622(80)80221-0
[Indexed for MEDLINE]

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