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Nature. 1978 Apr 6;272(5653):506-10.

Three-dimensional reconstruction of the fibres of sickle cell haemoglobin.

Abstract

Three-dimensional reconstruction of electron micrographs of the 20-nm diameter fibres of HbS reveals an inner helical core of four strands surrounded by an outer helix of 10 strands to give a total of 14 strands. The strands are arranged with roughly hexagonal packing to produce an unusual helical structure which features a variety of intermolecular contacts and a non-circular cross section.

PMID:
692655
DOI:
10.1038/272506a0
[Indexed for MEDLINE]

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