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J Med Chem. 1980 Oct;23(10):1134-6.

Ivermectin, a new broad-spectrum antiparasitic agent.

Abstract

22,23-Dihydroavermectin B1, ivermectin, derived from avermectin B1 by selective hydrogenation using Wilkinson's homogenous catalyst [Ph3P)3RhCl], was shown to be a highly effective drug for the treatment of a wide variety of metazoan parasitic diseases in animals.

PMID:
6893469
DOI:
10.1021/jm00184a014
[Indexed for MEDLINE]

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