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Cell Tissue Res. 1982;227(3):563-8.

A cell line (HBL-100) established from human breast milk.

Abstract

A continuous cell line (HBL-100) was obtained from primary cultures of cells derived from an early lactation sample of human milk. There was no evidence of a breast lesion in the milk donor. Karyotype analysis showed that all metaphases contained human chromosomes including a large acrocentric marker chromosome. Both desmosomes and cytoplasmic tonofibrils were observed during early passage. HBL-100 cells exhibited several characteristics of transformation including the ability to form colonies in soft agar, an aneuploid chromosome complement, and continuous growth.

PMID:
6891286
DOI:
10.1007/bf00204786
[Indexed for MEDLINE]

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