Format

Send to

Choose Destination
See comment in PubMed Commons below
Science. 1982 Dec 10;218(4577):1075-82.

New chemistry of an old molecule: cis-[Pt(NH3)2Cl2].

Abstract

The discovery that cis-diamminedichloroplatinum(II) (cis-DDP) has clinically useful antitumor properties and can form platinum blues spawned an extensive investigation of its chemistry in water. Several new molecules have been synthesized, some rather old ones have been characterized for the first time, and clues have begun to emerge about the chemical interaction of cis-DDP with its likely biological target, DNA.

PMID:
6890712
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Support Center