Send to

Choose Destination
See comment in PubMed Commons below
Int J Radiat Oncol Biol Phys. 1983 Sep;9(9):1391-5.

Transperineal percutaneous iridium-192 implant of the prostate.


Interstitial implantation of radioisotopes has become an increasingly popular modality for the management of localized adenocarcinoma of the prostate. Despite the recognized disadvantages, including technical difficulties of accurate seed placement, uncorrectable dose, inhomogeneities in implant volume, limitations in the range of irradiation, and radiation exposure to personnel handling active sources, permanent implantation of either iodine-125 or gold-198 seeds has been widely advocated. A technique of transperineal implantation with afterloading that circumvents many of the problems associated with permanent types of implants is described. Three thousand rad of external beam irradiation was administered three weeks after the implant. Twenty-five patients with clinically localized adenocarcinoma of the prostate were treated with excellent normal tissue tolerance and no major complications. This technique offers excellent control over the implant volume, dose distribution, and radiation exposure to personnel.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center