Guinea pigs were anesthetized by epidural injection of xylocaine 20 minutes following the administration of chlorpromazine, cortisone, and hydrocortisone. The right adrenal gland was removed aseptically by careful blunt dissection. Ten milliliters of warm saline containing tobramycin was given subcutaneously at the conclusion of the surgery, and the guinea pig was returned to a recovery cage containing a heating pad. Ten days later, the left adrenal gland was removed using similar procedures.