Send to

Choose Destination
See comment in PubMed Commons below
Invest Ophthalmol Vis Sci. 1983 Jan;24(1):47-51.

Laser Doppler Velocimetry study of the effect of pure oxygen breathing on retinal blood flow.


The noninvasive Laser Doppler Velocimetry (LDV) technique was used in normal volunteers to determine retinal blood flow, F, during pure oxygen breathing at atmospheric pressure. Changes in blood flow were calculated based on Poiseuille relation, F = (pi D2/4) X Vmax, where Vmax is the red blood cell maximum or center-line velocity and D, the diameter of the vessel at the site of the LDV recordings. After five minutes of pure oxygen breathing, Vmax decreased by about 53%, vessel diameter by 12%, and retinal blood flow by about 60%. In arteries, pulsatility of red blood cell velocity (Vmax, systole/Vmax, diastole) during the cardiac cycle increased by about 10%. Decrease in red blood cell velocity was detectable within 1-1 1/2 min. From these LDV flow measurements and the changes in retinal mean circulation time (MCT) reported by other investigators, based on the relation F = v/MCT, a 45% decrease in retinal blood volume (v) during 100% O2 breathing was obtained.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Silverchair Information Systems
    Loading ...
    Support Center