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Comput Biol Med. 1984;14(2):217-23.

Analysis of circadian rhythms by fitting a least squares sine curve.

Abstract

A method that fits a least squares sine curve to both point and averaged time series data is described. The method includes a full regression analysis and extends the current "cosinor" approach. Developments include estimation of the linear trend and fitting secondary wave forms.

PMID:
6723267
[Indexed for MEDLINE]
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