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Am J Cardiol. 1984 Feb 1;53(4):586-9.

Augmentation of atrial contribution to left ventricular inflow with aging as assessed by intracardiac Doppler flowmetry.


The influence of aging on the left ventricular (LV) function in diastole was investigated from the aspect of the mitral inflow pattern using 2-dimensional Doppler echocardiography. The subjects for the investigation were 69 persons who were diagnosed as healthy by a checkup examination. The peak velocity in the rapid filling phase and that in the atrial contraction phase tended to decrease and to increase with aging, respectively. However, these tendencies were not statistically significant. However, the ratio of the atrial contraction phase to the rapid filling phase showed a significant increase with aging (r = 0.82, p less than 0.001). Therefore, it is considered that the mitral flow conditions are influenced by aging. The result obtained is also interpreted to mean that the LV distensibility in early diastole is impaired with aging and that the contribution of the atrial contraction to LV filling is compensatorily augmented.

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