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Neurosci Lett. 1983 Dec 2;42(2):131-5.

Extrinsic innervation of the rat pancreas: demonstration of vagal sensory neurones in the rat by retrograde tracing.


The extrinsic innervation of the rat pancreas was examined using retrograde tracing with the fluorescent dye True Blue. Retrogradely-labelled cell bodies were seen bilaterally in the nodose ganglia, and in the spinal ganglia at levels T6-L2. Labelled cells were also seen in the dorsal motor nucleus of the vagus, the nucleus ambiguus and the coeliac ganglion. Our results provide new and direct evidence for a vagal sensory innervation of the pancreas.

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