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Can J Microbiol. 1983 Sep;29(9):1230-3.

Arginine biosynthesis in Legionella pneumophila: absence of N-acetylglutamate synthetase.

Abstract

Legionella pneumophila was unable to grow in a chemically defined medium without arginine because it could not carry out the first step in the biosynthetic pathway, the conversion of glutamate to N-acetylglutamate. All strains examined could grow when N-acetylglutamate (or other later arginine precursors) were substituted for arginine. No activity corresponding to N-acetylglutamate synthetase could be detected in cell extracts of L. pneumophila.

PMID:
6652583
[Indexed for MEDLINE]

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