21-Hydroxypregna-1,4-diene-3,11,20-trione: a biliary metabolite of a cartilaginous fish, Raja sp

Steroids. 1978 Apr;31(4):573-82. doi: 10.1016/0039-128x(78)90038-7.

Abstract

21-Hydroxypregna-1,4-diene-3,11,20-trione was isolated from skate bile and as an in vivo metabolite of 3H-1alpha-hydroxycorticosterone. Identity was established by chromatography and derivatization to constant 3H/14C ratio and mass spectrometry of the 20,21-acetonide. The new steroid was present in the free form and as the glucuronoside.

MeSH terms

  • Animals
  • Bile / analysis*
  • Corticosterone / analogs & derivatives
  • Corticosterone / metabolism
  • Fishes
  • Ketosteroids / analysis
  • Mass Spectrometry
  • Pregnadienes / analysis*

Substances

  • Ketosteroids
  • Pregnadienes
  • 21-hydroxypregna-1,4-diene-3,11,20-trione
  • Corticosterone