5'-Terminal sequence of the mRNA of mouse whey acidic protein contains three possible sites of interaction with 18S rRNA

Biochem Biophys Res Commun. 1983 Oct 14;116(1):167-72. doi: 10.1016/0006-291x(83)90396-0.

Abstract

The mRNA sequence of whey acidic protein, a major mouse milk protein, was cloned in full length. The sequence analysis of the cDNA clones revealed that the mRNA contains a 28 nucleotide-long 5'-noncoding region. Three different portions of this region were identified as possible sites of interaction with the 3'-end of 18S rRNA that may facilitate efficient rate of translation of the mRNA.

MeSH terms

  • Animals
  • Base Sequence
  • Caseins / genetics
  • Female
  • Gene Expression Regulation
  • Mammary Glands, Animal / physiology
  • Mice
  • Milk Proteins / genetics*
  • Nucleic Acid Conformation
  • Nucleic Acid Hybridization
  • RNA, Messenger / genetics*
  • RNA, Ribosomal / genetics*

Substances

  • Caseins
  • Milk Proteins
  • RNA, Messenger
  • RNA, Ribosomal
  • whey acidic proteins