We report what we believe to be the first proven marked concomittant elevations in serum creatine kinase (CK) and lactic dehydrogenase (LD) in a patient with bowel necrosis. The necrosis was the result of infarction secondary to bowel strangulation. The serum from this patient showed elevation of total CK activity resulting from an abnormal amount of MM, MB, and BB isoenzymes with LD2, LD3, and LD5 yielding 18 per cent, 19 per cent, and 29 per cent, respectively, of the total LD activity.