Abstract
The malignant potential of the hamartomatous polyps in Peutz-Jeghers syndrome has been debated. Although this is a very rare event, these polyps can undergo carcinomatous transformation, as demonstrated by this report of a 37-year-old man with well-documented Peutz-Jeghers syndrome who developed an invasive grade 2 adenocarcinoma on the surface of a hamartomatous polyp in the rectum.
MeSH terms
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Adenocarcinoma / pathology*
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Adenocarcinoma / surgery
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Adult
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Hamartoma / pathology*
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Hamartoma / surgery
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Humans
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Intestinal Polyps / pathology*
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Intestinal Polyps / surgery
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Male
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Neoplasm Invasiveness
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Neoplasms, Multiple Primary / pathology*
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Neoplasms, Multiple Primary / surgery
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Peutz-Jeghers Syndrome / complications*
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Rectal Neoplasms / pathology*
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Rectal Neoplasms / surgery