Adenocarcinoma of the rectum arising in a hamartomatous polyp in a patient with Peutz-Jeghers syndrome

Dig Dis Sci. 1983 Nov;28(11):1047-51. doi: 10.1007/BF01311735.

Abstract

The malignant potential of the hamartomatous polyps in Peutz-Jeghers syndrome has been debated. Although this is a very rare event, these polyps can undergo carcinomatous transformation, as demonstrated by this report of a 37-year-old man with well-documented Peutz-Jeghers syndrome who developed an invasive grade 2 adenocarcinoma on the surface of a hamartomatous polyp in the rectum.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / pathology*
  • Adenocarcinoma / surgery
  • Adult
  • Hamartoma / pathology*
  • Hamartoma / surgery
  • Humans
  • Intestinal Polyps / pathology*
  • Intestinal Polyps / surgery
  • Male
  • Neoplasm Invasiveness
  • Neoplasms, Multiple Primary / pathology*
  • Neoplasms, Multiple Primary / surgery
  • Peutz-Jeghers Syndrome / complications*
  • Rectal Neoplasms / pathology*
  • Rectal Neoplasms / surgery