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Theor Popul Biol. 1983 Jun;23(3):300-13.

The effect on neutral gene flow of selection at a linked locus.

Abstract

The effect on gene flow at a neutral locus of a selective cline at a linked locus is investigated. A diffusion approximation for a two-locus island model is derived in which only one locus is subject to selection. The moments of the stationary distribution are obtained and compared to the corresponding moments from a one-locus, neutral island model. This comparison yields an effective migration rate. The effective migration rate is always less than the actual migration rate, but this effect is seen to be small for weak selection and loose linkage in the case of adult migration. The importance of selection at linked loci to the question of genetic differentiation in a subdivided population is discussed.

PMID:
6623407
[Indexed for MEDLINE]
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