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J Prosthet Dent. 1984 May;51(5):617-23.

Effect of dental amalgam and nickel alloys on T-lymphocytes: preliminary report.


Preliminary data suggest that dental amalgam and dental nickel alloys can adversely affect the quantity of T-lymphocytes. Human T-lymphocytes can recognize specific antigens, execute effector functions, and regulate the type and intensity of virtually all cellular and humoral immune responses. Normal immune function depends on a proper quantity, quality, and ratio of T-lymphocyte helper and suppressor subsets. Further research may determine the frequency and magnitude of T-lymphocyte reduction and alteration by dental materials.

[Indexed for MEDLINE]

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