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Am J Clin Pathol. 1984 Jan;81(1):85-8.

Clinical significance of serotype, biotype, and beta-lactamase production of respiratory isolates of Hemophilus influenzae.

Abstract

The correlation between clinical significance and serotype, biotype, and beta-lactamase production of 101 respiratory isolates of Hemophilus influenza from nonbacteremic patients was determined. Six of 33 (18.2%) isolates from patients with definite or probable infection were serotypable; only two of 67 (3%) isolates from colonized patients were serotypable. Eight-seven and one-half per cent of the serotypable strains were biotypes I or IV; 78.8% of nonserotypable strains were biotypes II, III, or V. Biotype distribution among isolates from patients with definite or probable infection were similar to isolates from colonized patients. beta-lactamase production was not helpful in evaluating clinical significance. Nonserotypable H. influenzae is an important cause of nonbacteremic pneumonia in elderly men.

PMID:
6606978
DOI:
10.1093/ajcp/81.1.85
[Indexed for MEDLINE]

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