The endodontic access cavity is an essential component of the endodontic triad upon which all subsequent canal preparation and filling is based. It is probably the most frequently underemphasized aspect of endodontic therapy. This results in great clinical frustration and poor immediate and long-term results for the practitioner. The access cavity must provide clear and unobstructed access to each and every orifice and must be designed in such a way so as not to interfere with the often difficult intracanal procedures to follow. An understanding of root development, chamber, and canal anatomy will allow the practitioner to more easily debride and seal each canal through proper access cavity preparation.