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J Dent Res. 1984 Mar;63(3):452-4.

Neutrophil receptor modulation in the pathogenesis of periodontal diseases.

Abstract

The role of the neutrophil as a primary protective cell in the pathogenesis of periodontal disease has been well established. In this paper, the role of receptor modulation on the neutrophil surface is discussed as a possible mechanism for neutrophil functional abnormalities. Using localized juvenile periodontitis (LJP) as a model, the direct inhibition of neutrophils by bacterial products is discussed as a possible mechanism for local neutrophil dysfunction. In both disease processes, neutrophil receptor modulation plays a central role.

PMID:
6583245
DOI:
10.1177/00220345840630031701
[Indexed for MEDLINE]

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