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Nature. 1984 Oct 25-31;311(5988):716-21.

Cell type-specific activation of actin genes in the early amphibian embryo.

Abstract

Muscle actin genes are the earliest yet described to show cell type-specific activation in amphibian embryos. Gene-specific probes show that alpha-skeletal and alpha-cardiac actin genes start to be transcribed simultaneously at the end of gastrulation, but only in those regions of the mesoderm that subsequently form embryonic muscle. Their expression provides a molecular marker for early cell determination.

PMID:
6548550
DOI:
10.1038/311716a0
[Indexed for MEDLINE]

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