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Kosm Biol Aviakosm Med. 1984 Sep-Oct;18(5):50-4.

[Reactions of the lymphoid organs of the rat to acute stress in hypokinesia].

[Article in Russian]


Female rats long exposed to hypokinesia were then subjected to an acute stress. In this situation the thymus and spleen were examined. The destructive process in the thymus increased in spite of its hypoplasia. This can be attributed to a greater production of corticosteroids by the adrenals caused by the chronic stress. At the same time the white pulp of the spleen decreased insignificantly because it contained no lymphocytes capable to migrate by the time of the acute stress-effect. It is concluded that enhanced destruction of lymphocytes in the thymus in response to an acute stress can be regarded as a diagnostic test of the adrenal state during a chronic stress-effect, including hypokinesia.

[Indexed for MEDLINE]

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