Synthetic skin CODOGARD produced by the Research and Development Centre of the Knitting Industry in Lódź was applied in 125 cases of the shank varicose ulcer treated in the Clinic of General Surgery of the Warsaw Medical Academy. Two different types of CODOGARD were used for evaluation: the first one without antibacterial dripping, and the second one with antibacterial dropping Sterinol. On the basis of achieved results it was established that CODOGARD was a successful medicine for the crus varicose ulcer. It causes faster cleaning away of the pus. It was observed that CODOGARD with Sterinol dripping was more effective. Taking into account the fact that the application of CODOGARD is easy, it should be widely used in surgical out patient's departments.