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Immunogenetics. 1984;20(4):433-42.

Identification of class I major histocompatibility complex encoded molecules in the amphibian Xenopus.

Abstract

Class I-like molecules have been immunoprecipitated from Xenopus leukocytes and erythrocytes with alloantisera directed against major histocompatibility complex (MHC)-linked antigens. The heavy chains, depending on the allele examined, have molecular weights of 40 000-44 000 of which 3000 daltons are asparagine-linked carbohydrates, probably present as one N-linked glycan. The presumed analogue of beta 2-microglobulin has a molecular weight of 13 000 and bears no asparagine-linked glycans. Family studies show that the heavy chains are encoded by genes residing in or closely linked to the MHC.

PMID:
6490110
DOI:
10.1007/bf00345617
[Indexed for MEDLINE]

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