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Physiol Behav. 1984 Apr;32(4):677-81.

Together intracranial angiotensin and systemic mineralocorticoid produce avidity for salt in the rat.


Rats that have no need for sodium will run to small rewards of 3% NaCl solution in a runway after they have been treated with both a mineralocorticoid and angiotensin II. When given alone at the low doses used here, neither the mineralocorticoid nor the angiotensin produce the behavior. This result encourages the idea that it is a synergy of the hormones of sodium conservation, angiotensin and aldosterone, that apprises the brain of the need for salt and generates the appetite for the taste of salt.

[Indexed for MEDLINE]

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