Format

Send to

Choose Destination
Rev Infect Dis. 1984 Jul-Aug;6(4):428-31.

Lipopolysaccharides: structural principles and biologic activities.

Abstract

Structural principles of the three regions of the lipopolysaccharide molecule are briefly discussed. One of the recently available, chemically synthesized lipid A analogues has been tested for biologic activities. The preparation was found to be toxic, pyrogenic, and mitogenic. The amounts, however, needed for expression of effects similar to those of lipid A were about 500 times higher. These investigations are aimed at verifying the proposed structure of lipid A and at evaluating structure-activity relationships.

PMID:
6474001
DOI:
10.1093/clinids/6.4.428
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center