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Neurosci Lett. 1981 Feb 23;22(1):75-8.

Histamine hyperpolarizes hippocampal neurones in vitro.

Abstract

The postsynaptic effect of histamine and impromidine, an H2-receptor agonist on CA1 pyramidal and dentate granule cells in the hippocampal slice of the rat is a hyperpolarization. Depolarizations are indirectly mediated. It is suggested that the hyperpolarization is generated by a conductance increase to potassium ions in the dendrites.

PMID:
6452591
[Indexed for MEDLINE]
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