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S Afr Med J. 1980 Aug 2;58(5):197-200.

The origin of Huntington's chorea in the Afrikaner population of South Africa.

Abstract

Huntington's chorea is prevalent among the Afrikaner population of South Africa. The origin of the gene for the disorder in this population group has been traced over 14 generations from the present time to the days of the first free burghers at the Cape of Good Hope. Over 200 affected individuals in more than 50 supposedly unrelated families have been found to be ancestrally related through a common progenitor in the 17th century.

PMID:
6447365
[PubMed - indexed for MEDLINE]
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