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J Rheumatol. 1983 Dec;10(6):954-6.

beta 2 microglobulin plasma levels reflect disease activity in rheumatoid arthritis.


Elevated plasma levels of beta 2 microglobulin have been described in rheumatoid arthritis (RA) but their relationship to disease activity is unclear. In patients treated for 6 months with auranofin (AF) there was a significant fall (p less than 0.05) in beta 2M levels pari passu with improvement in disease activity as measured by a fall in C-reactive protein. In addition, 26 patients with mild RA had beta 2M levels within the normal range. It is concluded that beta 2M plasma levels reflect disease activity in RA.

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