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Atherosclerosis. 1984 Dec;53(3):265-71.

Monocytic origin of foam cells in human atherosclerotic plaques.

Abstract

Foam cells in 4 human atherosclerotic plaques reacted with 3 rat monoclonal antibodies directed against T.200 ('anti-leucocyte common' antibody), HLA-Class II molecules and macrophage cytoplasm, respectively. Smooth muscle cells did not react. The results support the view that foam cells are monocyte-derived macrophages.

PMID:
6397199
DOI:
10.1016/0021-9150(84)90127-8
[Indexed for MEDLINE]

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