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Biochem Biophys Res Commun. 1984 Sep 17;123(2):528-34.

Necessity of polyamines for maximum in vivo synthesis of beta beta' subunits of RNA polymerase.

Abstract

The possibility that polyamines can stimulate the in vivo synthesis of beta beta' subunits of RNA polymerase has been examined through the use of a polyamine-requiring mutant of Escherichia coli. Results from autoradiographic estimation and activity measurement of RNA polymerase in cell extracts prepared from polyamine starved and unstarved bacteria showed that polyamines stimulate the synthesis of beta beta' subunits of RNA polymerase 2- to 3.6-fold.

PMID:
6385968
DOI:
10.1016/0006-291x(84)90261-4
[Indexed for MEDLINE]

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