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Biochem Biophys Res Commun. 1984 Jul 18;122(1):103-10.

The isolation and characterization of an insulin-releasing tetrapeptide from urines of patients with lipoatrophic diabetes.

Abstract

The tetrapeptide pyroGlu-Glu-Asp-GlyOH and its gamma-amide have been isolated from the urines of lipodystrophic patients with insulin-resistant diabetes. Both peptides induce insulin release only at high blood glucose levels.

PMID:
6378198
[Indexed for MEDLINE]

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