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Biomed Biochim Acta. 1984;43(3):K6-8.

In vivo injection of dipyridamole stimulates the synthesis of prostacyclin-like substances in human varicose veins.

Abstract

The influence of dipyridamole, given by a bolus injection (30 mg i. v.) on the synthesis of prostacyclin-like substances (PGI2-LS) in human shank varicose veins was investigated. The pretreatment with dipyridamole enhances the second step in PGI2 biosynthesis (transformation of endoperoxide to PGI2) in these preparations.

PMID:
6378192
[PubMed - indexed for MEDLINE]
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