Send to

Choose Destination
See comment in PubMed Commons below
Peptides. 1983 Mar-Apr;4(2):231-8.

The coexistence and release of bovine pancreatic polypeptide-like immunoreactivity from noradrenergic superior cervical ganglia neurons.


The coexistence of bovine pancreatic polypeptide-like (BPP) immunoreactivity within the cell bodies and axons of the superior cervical ganglia (SCG) was studied. Adjacent sections stained by the indirect immunofluorescence technique for either BPP or dopamine-beta-hydroxylase (DBH) revealed that virtually all (90-95%) SCG cells contained DBH and a subpopulation (30-50%) also contained BPP. Ligation of the pre- and postganglionic nerves of the SCG demonstrated BPP-positive fibers emanating from the SCG via both axonal trunks. BPP-containing fibers were also observed entering the SCG via the preganglionic nerve. The peptide was co-released with catecholamine by electrical stimulation of the preganglionic cervical sympathetic nerve trunk, but was not effected by reserpine. The extensive distribution and unique coexistence of a PP-like peptide with peripheral sympathetic nerves suggests a neuromodulatory role in autonomic functions.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center