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J Immunol Methods. 1983 Jul 15;61(2):253-7.

Lack of specificity of the C3-opsonized zymosan reagent for the assay of membrane complement receptors.


C3-opsonized zymosan particles (C3-zymosan) have been utilized as reagents for detection of C3 receptor bearing cells. However, in this communication we present evidence that C3-zymosan particles are not useful for this purpose in some species with certain macrophage populations because of non-specific binding of unopsonized zymosan.

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