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Nature. 1984 May 3-9;309(5963):30-3.

Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule.


The ability of fibronectin to bind cells can be accounted for by the tetrapeptide L-arginyl-glycyl-L-aspartyl-L-serine, a sequence which is part of the cell attachment domain of fibronectin and present in at least five other proteins. This tetrapeptide may constitute a cellular recognition determinant common to several proteins.

[Indexed for MEDLINE]

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