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J Gen Physiol. 1984 Feb;83(2):133-42.

Analysis of sodium current fluctuations in the cut-open squid giant axon.

Abstract

Patch pipettes were used to record the current arising from small populations of sodium channels in voltage-clamped cut-open squid axons. The current fluctuations associated with the time-variant sodium conductance were analyzed with nonstationary statistical techniques in order to obtain an estimate for the conductance of a single sodium channel. The results presented support the notion that the open sodium channel in the squid axon has only one value of conductance, 3.5 pS.

PMID:
6325579
PMCID:
PMC2215630
[Indexed for MEDLINE]
Free PMC Article

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