Format

Send to

Choose Destination
See comment in PubMed Commons below
Nature. 1983 Oct 13-19;305(5935):605-8.

Structural and immunological similarities between simian sarcoma virus gene product(s) and human platelet-derived growth factor.

Abstract

The predicted amino acid sequence of the simian sarcoma virus (SSV) transforming gene product, p28sis, closely corresponds to that of human platelet-derived growth factor (PDGF). We demonstrate that p28sis rapidly undergoes a series of discrete processing steps including dimer formation and proteolytic digestion to yield molecules structurally and immunologically resembling biologically active PDGF.

PMID:
6312326
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center