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Neurosci Lett. 1981 Jul 17;24(3):243-6.

A "receptor" for protons in small neurons of trigeminal ganglia: possible role in nociception.

Abstract

Neurons of the rat's trigeminal ganglion were enzymatically isolated and investigated under the conditions of intracellular perfusion and voltage clamp. Recently discovered proton-activated sodium conductance was found in about half of the neurons. The majority of these proton-sensitive neurons (74%) were less than 26 micrometer in diameter, whereas most of the proton-insensitive cells (75%) were larger than 26 micrometer in diameter. The possibility is discussed that the small proton-sensitive neurons may participate in nociception.

PMID:
6269026
DOI:
10.1016/0304-3940(81)90164-6
[Indexed for MEDLINE]

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