Format

Send to

Choose Destination
Cancer Treat Rep. 1976 May;60(5):535-9.

Chemotherapy versus chemoimmunotherapy of head and neck cancer: report of a randomized study.

Abstract

Thirty-four patients with recurrent squamous cell carcinoma of the head and neck were randomized to receive the five-drug chemotherapy regimen BACON (bleomycin, adriamycin, CCNU, vincristine [Oncovin], and mechlorethamine [nitrogen mustard]; 14 patients) or the same regimen plus bacillus Calmette-Gu erin (BCG) by scarification (20 patients). The majority of both patient groups had received prior surgery and radiation. The patients treated with BACON plus BCG experienced a significantly longer survival (P = 0.014) than those treated with BACON alone. There were five drug-related deaths, and eight other patients required hospitalization for treatment of drug-related morbidity.

PMID:
62613
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center