The nucleotide sequence of the human beta-globin gene

Cell. 1980 Oct;21(3):647-51. doi: 10.1016/0092-8674(80)90428-6.

Abstract

We report the complete nucleotide sequence of the human beta-globin gene. The purpose of this study is to obtain information necessary to study the evolutionary relationships between members of the human beta-like globin gene family and to provide the basis for comparing normal beta-globin genes with those obtained from the DNA of individuals with genetic defects in hemoglobin expression.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Cloning, Molecular
  • Codon
  • DNA / genetics
  • DNA Restriction Enzymes
  • Genes*
  • Globins / genetics*
  • Humans
  • Polymorphism, Genetic

Substances

  • Codon
  • Globins
  • DNA
  • DNA Restriction Enzymes

Associated data

  • GENBANK/J00093
  • GENBANK/J00094
  • GENBANK/J00096
  • GENBANK/J00158
  • GENBANK/J00159
  • GENBANK/J00160
  • GENBANK/J00161
  • GENBANK/J00162
  • GENBANK/J00163
  • GENBANK/J00164
  • GENBANK/J00165
  • GENBANK/J00166
  • GENBANK/J00167
  • GENBANK/J00168
  • GENBANK/J00169
  • GENBANK/J00170
  • GENBANK/J00171
  • GENBANK/J00172
  • GENBANK/J00173
  • GENBANK/J00174
  • GENBANK/J00175
  • GENBANK/J00177
  • GENBANK/J00178
  • GENBANK/J00179
  • GENBANK/K01239
  • GENBANK/K01890
  • GENBANK/K02544
  • GENBANK/M18047
  • GENBANK/M19067
  • GENBANK/X00423