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Yale J Biol Med. 1984 Jul-Aug;57(4):595-8.

Cellular immune findings in Lyme disease.

Abstract

From 1981 through 1983, we did the first testing of cellular immunity in Lyme disease. Active established Lyme disease was often associated with lymphopenia, less spontaneous suppressor cell activity than normal, and a heightened response of lymphocytes to phytohemagglutinin and Lyme spirochetal antigens. Thus, a major feature of the immune response during active disease seems to be a lessening of suppression, but it is not yet known whether this response plays a role in the pathophysiology of the disease.

PMID:
6240164
PMCID:
PMC2590033
[Indexed for MEDLINE]
Free PMC Article

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