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Am J Dis Child. 1978 Jan;132(1):37-9.

Toxic encephalopathy related to antihistamine-barbiturate antiemetic medication.


A toxic encephalopathy characterized by depressed level of consciousness, marked irritability, and ataxia developed in seven children, 5 years of age and younger, following administration of an antiemetic combination of pentobarbital and pyrilamine maleate. Three of the seven patients were given a dosage of medication and exceeding the manufacture's recommendation. All seven patients recovered without sequelae.

[Indexed for MEDLINE]

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