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Rev Infect Dis. 1984 Sep-Oct;6(5):619-24.

Capsular polysaccharides of Cryptococcus neoformans.

Abstract

Polysaccharides of Cryptococcus neoformans are considered to have a role in the virulence of this encapsulated fungus. The structure has been determined for the most abundant polysaccharide, a glucuronoxylomannan of varying xylose and ester content. The structural complexity of the capsular material increases from serotype D to A to B to C, but even for the simplest capsule (type D), the immunodeterminants seem to occur only on the side chains. The interactions of some of these groups with antibodies is discussed.

PMID:
6209768
DOI:
10.1093/clinids/6.5.619
[Indexed for MEDLINE]

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