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Eur J Biochem. 1981 Dec;120(3):519-22.

Synthesis in vitro and translocation of apolipoprotein AI across microsomal vesicles.


Apolipoprotein AI of rats has been synthesized in a cell-free wheat germ system and cotranslationally translocated into dog pancreas microsomal vesicles. Translocation is accompanied by cleavage of a signal sequence of 18 amino acid residues and is dependent on the recently purified signal recognition protein.

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